Most early Ebola symptoms are indistinguishable from malaria, typhoid, or influenza. The two-phase clinical picture, the warning signs, and what to do if you may have been exposed.
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What are the symptoms of Ebola?
Sudden fever, severe headache, muscle pain, and fatigue, 2 to 21 days after exposure. Most cases progress in 5 to 7 days.
Early Ebola symptoms appear suddenly: high fever (usually above 38.5°C),
intense headache, muscle and joint pain, profound fatigue, and sore
throat. This "dry phase" typically lasts 3 to 5 days and overlaps
heavily with malaria, typhoid, and influenza, which is why laboratory
testing is required to confirm Ebola. A "wet phase" follows, with
vomiting, diarrhoea, abdominal pain, hiccups, rash, and sometimes
unexplained bleeding (gums, eyes, injection sites, stool). The
incubation period from exposure to first symptoms ranges 2 to 21
days, with most cases developing symptoms within 8 to 10 days.
Ebola is not contagious before symptoms begin.
This page is editorial reference, not medical advice. If you may have
been exposed to Ebola, contact your local public health authority before
visiting a clinic so triage can prepare isolation procedures.
Phase 1 · Early "dry" phase (days 1–4)
· Sudden onset of fever (often above 38.6 °C)
· Severe fatigue and malaise
· Muscle pain and joint aches
· Headache
· Sore throat
· Loss of appetite
These symptoms are indistinguishable from many common tropical infections. Laboratory testing is required to confirm or rule out Ebola.
Phase 2 · Progressive "wet" phase (days 5+)
· Vomiting and abdominal pain
· Profuse watery diarrhoea (a major cause of dehydration death)
· Rash on the trunk
· Impaired liver and kidney function
· In a minority of patients: bleeding from the gums, bloody stools, blood in the eyes
Mortality is driven primarily by fluid and electrolyte loss and by septic complications, not by the classic "haemorrhagic" presentation that the older name (Ebola haemorrhagic fever) implies.
Differential diagnosis
Most patients presenting with fever in a region of active Ebola transmission do not have Ebola. The clinical task is to identify the much smaller subset who do. Common alternatives:
Condition
Overlapping symptoms
Distinguishing features
Diagnostic confirmation
Malaria
Fever, headache, fatigue, muscle pain
Cyclical fever, splenomegaly; common across DRC and Uganda regardless of Ebola activity
Rapid diagnostic test or microscopy
Typhoid fever
Fever, abdominal pain, fatigue
Step-ladder fever pattern, relative bradycardia, rose spots
Blood culture
Lassa fever
Fever, sore throat, retro-orbital pain
Geographic distribution centred on West Africa; bleeding less prominent
PCR / IgM
Marburg virus disease
All Ebola-like symptoms
Clinically indistinguishable from Ebola; require lab differentiation
PCR with filovirus panel
Dengue fever
Fever, headache, muscle pain
Retro-orbital pain, biphasic fever, leukopenia
NS1 antigen or PCR
Yellow fever
Fever, jaundice, vomiting
Jaundice prominent; vaccine history relevant
IgM serology / PCR
If you may have been exposed
Isolate immediately in a separate room with a closed door if possible.
Call ahead before going to any healthcare facility. Walking into an unprepared clinic risks transmission to staff and other patients.
Mention the exposure: specify which country, which province, which dates, and any contact with sick or deceased persons or with bats and primates.
Do not self-medicate with antibiotics or antimalarials before laboratory testing; this can mask diagnosis.
In Germany dial 112; in the UK dial 111; in the US dial your state health department. Other countries: contact the WHO emergency number for your region.
This page is reference material, not a substitute for clinical evaluation by a qualified healthcare professional.